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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2d2984cdae542f6b0cd3a17d323786b4fdf4d75f5d7c20c9419a55d8d91f335' 
  AND token = 'XxJ6z4CAxg1X/tsNddBVZDuRVf1HcBuA3ZIKxS5zzLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}