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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3725bffb9c8464fd9dd4b06789095b97d3b5984f6ae8e97fa48f76b12cddd756' 
  AND token = 'bA5dYkilEpdYNmt1DCZtW+ecRV5EqlEJyaYO/T0VahE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}