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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a84a2c286be6f418d35bb2d5fbfa76cf2673fb30ef1b6d41541041e4485e85c4' 
  AND token = 'YTPBSOzgtYmGh9faz8Z0IgxIo6jAPjm8gD5HkzlZuOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}