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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bbe063a88d5b6d32e899e4e477e9374995f4b23a2defded2882ba6b6eb90758' 
  AND token = 'XSghEedOTMPQiNfuwAjeXn6LtzhUD3f3+EJoamd7ZJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}