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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '049598f08c908c133ea596fd0f34d9a3b10d447638951d4b06a7f4dfc8bd610e' 
  AND token = '3jNAotL93I0XmOewAPR7n62hUnM4a19W141ZrTscD3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}