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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2af1e3bfdc3587c8a80cad3634e0c78a9b06542e3c5f86c6d5fbd429a1e74a03' 
  AND token = 'D7eoUQo8l2MLsyIrj7IzBHjEWdU3qMgpOGzStzwVC1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}