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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1431c23b61a2134c0dcf78dd98710c2e14bac82491a7a399e2bdf25ed2d7a594' 
  AND token = '1AS3LO3lYYE5xps2yrMKyI7/PKZAo2Rmy2ogUFKzwAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}