SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be7c603ed7320d252575f089cb3e83f6c6195c7a0efb440a0a66b53c1d2e39a8' 
  AND token = 'MkeMdZhk9dF8318PJsScXSeP88mRG47QIjgY5rGwEoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}