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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48ff11acb57005b340c43edd20144f696b3873102f5251ce9b0819fa7720754c' 
  AND token = 'kE9RAdbljd4e5Xrv33hqZlP7oNsbclfxIDZ2rCBhyAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}