SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8a9a7679c171a990df49891f4acee5da0e64533b0d3a7c865e9a2b886fd792a' 
  AND token = 'pIFJY2DsnLuLVrncrvZp2lnDFadbENp4QHTAf9zyRoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}