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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e52bc4e0cd2e039fe94f059b53b41ae573a61062c1ea071b5a7d03452e88bb29' 
  AND token = 'sRPR1IRPsLg3uIh+2rwFEl9YxJZDvhcOirBUzhe2cXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}