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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c73b94e48298ab0e9400bb7f887cfea488de5b9534948c7a4e76c48eba8a5c74' 
  AND token = 'oqYlArOvXH0Lrfi3KnMold1D/oq/ZLs8OCCe+C7Y0x8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}