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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8afbcc44e23a38c1c5121891b4589f347bba495929096a2c9437d8acfc217573' 
  AND token = 'HYYWNCyidfjF7GVG8RGvvupNxC40o72muErJR5UkYjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}