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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e8df59d7fb4525bebb2a48e6e9170d17c138e3ce2725928edc21c43f426fd6d' 
  AND token = '+w5MyN9I8Ez5GObWQ6nSjkSxnc4cx3G3O0q52DhQ078=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}