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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e8a15147bfd00849243ad2754c0731e3b60b39f9813db7d56b9a0ff6da339b9' 
  AND token = 'JmS8LnuX8bf81SddP+SD5tNPEfBo9OxAeHP5/a+4je0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}