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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd42ea87c82557933c342648fa1915d40f4eb4efd0485520a0e74d0dd00d9d7d8' 
  AND token = 'U5v8O5r0fthKWpPvu7j3TIyQeSRRJAxVcMmS0lj6gVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}