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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f5c75c5dfd7e27044190aced4135deb0e878e390f28640a9ae5fb794f395c61' 
  AND token = 'RbEG5inm8Y5Pc5LCU5VM+Ky/lnNZeU6qgHYoPlJLTr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}