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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '624bc0512da0f08c593158d930513cb7a2b564b9d98cdd538338d710d50a9b19' 
  AND token = 'WZn6S3AjJCqr2nKuigcP3AmC2x049lVUm8w7FFhbnhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}