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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f2a99c6c6a344497b7b44612cfd2c081d38011368dcd23a14fda8d4feb49c73' 
  AND token = 'OZwz33RfRZTtXqCeI1+3mMmh1VqP/U4djoXx2f0UP8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}