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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4ab6d52a681aa034b2222561d0a323c9cb4f0757eac5a453c8619154c77f1aa' 
  AND token = '0219UEmooXR8d9IGK+A/zsR+/kqmC+YsId9xeF+zH4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}