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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b4762b04b258873a7d207af0f00675b841b22a58c9dc8109509328a1cfe528b' 
  AND token = 'AM+mfzf+PbOkWAUyDmXWagKffn8o6AF1+B2dqFIC9aA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}