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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2148a2a5fbbac81e8621dc71d45be87f6ce3c77cbd0b16e59ecf735ddb9a3841' 
  AND token = 'f6nVyMb3fDUNn28eOSTZR/2I/z0V6g5g+PBm5+Q7+fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}