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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c7c21e6093939c649f7c6e8961b030910226d73b4b57ad3f2bee4889071c616' 
  AND token = 'bY0TRCP4T7KZUe3IixllKKRVYDNJ4yRqTUyNHh/VHFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}