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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c136aacd5f985e2810418ecf031c87d6eb23a6539133f507633cd3836af9a283' 
  AND token = 'r5wN0MHAoVyX1eEAFbDnfoVci0Y1i1np8R/XttZu3zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}