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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9054aeba4d2e0b3c741f71f4eeb2c5943bfbc45cc111a62599bcd3b82c417343' 
  AND token = 'hIG9z1nlJLYZmSaIyQrVls2t4fsOBrTV/sbpQ7JsDVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}