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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3ab55429a38ab79561bcbbc285ac31cb3fe7dd012ea072b9948812c6f611575' 
  AND token = 'ya+Gr7o5bT1+SqpbwUekysJt1w8EWmnntCJqtXS/htY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}