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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64b3ff97a1fabf97fb6a6f2af98b7da4d14d39b9d0608035d11b03d8178cbed8' 
  AND token = '1PyiHVS1tZupU0GFdqCrfHPqHkXtMtfN2d3u2ahWmH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}