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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68c4eed9d42b76466b18d077c158d32c28646f1434873a900512feefca0c63c1' 
  AND token = 'p0ExAZRDmXOn11O9xGmcznWzXN+O8r/PbMcwG+C3DaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}