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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4fbb373bca77be01f2a0140024e80462cffd878a983f3fe0161da0f5af9cacb' 
  AND token = 'F18A3wFcy50zcV5rBTra7eXPfkrZ5xKo7lier8N+0Yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}