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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe6575a6cdccc047c1d1f2090b271e81c9e9e8d303e6bac2c8cba26be28f1945' 
  AND token = '3aZwEe+uHd/r+XAKyu0nv6CIJ2oY84Y5Az5tIBvK1N4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}