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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '337df55d03b96b9941b3409da6a7f3afbc0f86685b5674f51b8446dfc8ee9c80' 
  AND token = 'vxB8HM/bkTanDzfZkItKSyuUjdNoLqPEw6NjOHS5U3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}