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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfcf3722881b6012bc975a586a71eedea195fb576a3db8fbfc4026c2faa541a1' 
  AND token = 'eSTi06IRAe2xRh3Vg/06UQFEFv9UFbius6jNi1q23q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}