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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1922f97a0129d8bd7298299249ba8fbd5b5443a3ebae2ce4d388636d412e418' 
  AND token = '/EQ4dx52DsF9rWmHj6Gtq3Pr+PMvEg2aTjM04zGnt7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}