SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '154122878ca51036910e37b37a46970bbdd2307564defd245a35eca2f460b020' 
  AND token = 'RyEFpZp0tUc/gIRooqtPC9VFUb+X1IFY+UioAIpFnn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}