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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a60968aa1cc169ff2d44397f72d8edda6de0b34597c540f9d13226fbfe59fd' 
  AND token = 'tpoIZNRqNcOBwDiLo0dTkmwAY7VwIJzf84DR/90ugy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}