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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0552f209ba728969ebf61029c34af1ac07e4a51339b9fb7a7b364302c34455f' 
  AND token = 'CFtLJmo5wI1wfsdJnEvN+Qw99+fcqrhFwockJBii1ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}