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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c3e3dc6e6f1f04b5a93e05310506a5f0dd95d3ed6dff8c000a02ce0dae39ce9' 
  AND token = 'xvfOX/+NCzotjpffveBe9DBdz8OlKelmg2ijigXcNmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}