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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45cd93436f0c62bcd707d4d410c764bac28ef8128e1c4bc5bf9d3987b1962248' 
  AND token = 'c2MH20qpMvya0YTn2XNuePU3kDi18klol+3fdk7lRLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}