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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a1ce46886b75435d411c8254a01bc6fcd3d25d0fff2bca04332d01640b00d9c' 
  AND token = '9Gv/D0LrX1eIgcmkb7DGzhMQ5rdXR+TAJeNJe2Ou9g8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}