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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aff6191cf7737e284cf0d28d8519a0667a74c2aac7247c9da1b600f02f4d1b92' 
  AND token = 'Uwp2sm/qEcLP0qdijTCAh9ridhQZQQA6Y8UPEpY4zw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}