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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b9e15f4fc726c3e97bd589dc567f648076d04d6653bb20d9be2b4c321b3d5a9' 
  AND token = 'lOhXec6WUkzkcw/Uk4yju1XZs4y6QSmjLlNq4Cgc4c0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}