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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91e5bdc8223fba1dee4aab156302b7b2f2ac2022d9df326108d446f02ff782c6' 
  AND token = 'HPmqQyTpJilQ0jpdAlODgg9mw7wbrxydgMRK4Z7Fsx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}