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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5c193df8e12f04cc56f5ff1e33c3e183a10bd59f63b929bd644a391b1bb4f81' 
  AND token = '9fiSSP7a5uOoOudeNWt6U3aDCxUe7Bsy94oqLzc+GBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}