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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec5428106d682f196bb4759936a4bd4f2c5a257929f447e813cf5490d87aab50' 
  AND token = 'pmwx9a7zkuRF19Af+dDe1/pu2ayRqb27lCTyVGAOEX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}