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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '496691ccf2c598e6550cad80cc6a8cd7b73920ed26f792319cf175ac184e7a58' 
  AND token = 'Yq+sLhs3hCEy20mbqYZiPS7KHaGgM8tIYgpgcyr9T2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}