SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b637ca089e3a303e2dab948fd6f28c10bda4d8c017e3992ddddf97edc5032274' 
  AND token = 'lD0HHLL2x9e1bm/RavIl8nHtatPg6ObPuAb1gAhJ/jI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}