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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d9a550dc4410fcfce3e3713d1308dd07da523f0cc8f4e994393fc6542275f0d' 
  AND token = '0M1uHA/REek+d9uIytM2PSsCxAPRZ7wU2fqwY83gHnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}