SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15d81e7103ed5634ba6d4ec597a1f6f9459a6c0bb464d445cf838072df22f17e' 
  AND token = 'tNfwYBsmNhyWmixzY052rlsnpIRjN0UIr6H9OVI1kT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}