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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65785b175f67434ce27e76a5d1b1d010c31d58254dd64acbe8f5c3218fdadeb' 
  AND token = '8WRZf4WWvFqTh2OmM14DF0QNP0K9fnBpWrYJ6BiGcYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}