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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50190a59325c5456ab1d3a32f852d7640a0b0006e38a87d1a3d6a2558d309877' 
  AND token = 'Zu7VrkjRS4kzDvT0CMRXpmCO/57PnnhuCsvP9ftBgO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}